MCQ on Mendelian Disorders in Humans: Biology is one of the most important and vital sections in NEET. It includes theories, descriptions, discoveries, diagrams, definitions, explanation of differences and relations. Most of the concepts covered in the NEET syllabus are from the NCERT syllabus of Class 11 & 12. Other related sources make up for the rest of the syllabus.

In this post we are providing you MCQ on Mendelian Disorders in Humans, which will be beneficial for you in upcoming NEET, AIIMS, JIPMER, PGIMER, CBSE Board, ICSE Board, Class 12th, 11th.

MCQ on Mendelian Disorders in Humans

Q1. Alpha 1 anti-trypsin deficiency is an autosomal recessive genetic disorder. What are the chances that any of the offspring do not express the disease phenotype if both parents are genotype (Aa)?
a) 100 per cent
b) 75 per cent
c) 50 per cent
d) 25 per cent

Q2. If the father in a family has a disease while the mother is normal, the daughters only are inherited by this disease and not the sons. Name this type of disease?
a) Autosomal recessive
b) Autosomal dominant
c) Sex-linked recessive
d) Sex-linked dominant

Q3. What will be the condition of the progeny if the father is normal, while the mother has one gene for haemophilia and one gene for colour blindness on one of the X chromosomes?
a) Only daughters are haemophilic and colour blind
b) Both sons and daughters will be haemophilic and colour blind
c) 50 per cent haemophilic and colour blind sons and 50% normal sons
d) 50 per cent haemophilic colour blind daughters and 50% colour blind daughters

Q4. Which of the following is a type of autosomal recessive genetic disorder?
a) Haemophilia
b) Skeletal dysplasia
c) Sickle cell anaemia
d) None of the above

Q5. Cystic fibrosis is an autosomal recessive genetic disorder. What are the chances that the child would have the disease if any one of the parent (either mother or father)is a carrier of the faulty cystic fibrosis gene (Cc)?
a) 100 per cent
b) 50 per cent
c) 25 per cent
d) 0 per cent

Q6. Which of the following is a trait of X-linked recessive?
a) Albinism
b) Haemophilia
c) Huntington’s disease
d) None of these

Q7. Which of the following disorder is also called the Royal disease?
a) Colour blindness
b) Haemophilia
c) Sickle cell anaemia
d) Alzheimer’s disease

Q8. The mode of inheritance for the trait – Fragile X syndrome is________.
a) X linked dominant
b) X linked recessive
c) Autosomal dominant
d) Autosomal recessive

Q9. Which of the following genotypes and phenotypes in a man may be the correct result of aneuploidy in sex chromosomes?
a) 22 pairs + Y females
b) 22 pairs + XY females
c) 22 pairs + XXY females
d) 22 pairs + XXXY females

Q10. Which of the following disorder is an example of point mutation?
a) Sickle cell anaemia
b) Down’s syndrome
c) Night blindness
d) Thalassemia

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By Team Learning Mantras