Humoral Immune Response – Class 12 | Chapter – 8 | Biology Short Notes Series PDF

Humoral Immune Response: Many of the bacteria that cause infectious disease in humans multiply in the extracellular spaces of the body, and most intracellular pathogens spread by moving from cell to cell through the extracellular fluids. The extracellular spaces are protected by the humoral immune response, in which antibodies produced by B cells cause the destruction of extracellular microorganisms and prevent the spread of intracellular infections. The activation of B cells and their differentiation into antibody-secreting plasma cells is triggered by antigen and usually requires helper T cells. 

Humoral Immune Response

  • It is mediated by B-cells.
  • Antibodies are formed in this.
  • In this antibodies are made used to identify antigens.
  • The antibodies produced by B-cells stick to the antigen.
  • It protects against extracellular viruses and bacteria.
  • It cannot eliminate tumour cells.
  • Only TH cells participate in humoral immunity.

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By Team Learning Mantras